Sermorelin
GHRH 1-29
A GHRH analog historically approved for diagnostic use and now commonly prescribed through compounding pharmacies.
At a glance
- Category
- Growth Hormone
- Half-life
- ~10 minutes
- Typical vial sizes
- 5 mg · 15 mg
Concentration by water volume
Pure arithmetic: the vial strength divided by the water added. The dose itself comes from your clinician, pharmacy, product instructions, or research protocol — enter it in the calculator below.
| Vial | Water added | Concentration | Per U-100 unit |
|---|---|---|---|
| 5 mg | 1 mL | 5 mg/mL | 50 mcg |
| 5 mg | 2 mL | 2.5 mg/mL | 25 mcg |
| 5 mg | 3 mL | 1.667 mg/mL | 16.667 mcg |
| 15 mg | 1 mL | 15 mg/mL | 150 mcg |
| 15 mg | 2 mL | 7.5 mg/mL | 75 mcg |
| 15 mg | 3 mL | 5 mg/mL | 50 mcg |
Storage
- Lyophilised (unmixed)
- Refrigerated.
- Reconstituted
- Refrigerate at 2–8°C.
What people log it against
Outcomes users commonly track alongside this compound. Listing them is not a claim that it produces them.
- Growth hormone support
- Sleep quality
Read alongside Sermorelin
Compounds this one is commonly compared with or mistaken for. Listing a pairing is not a suggestion to use them together.
- IpamorelinResearch use onlyBoth used as growth-hormone secretagogues through different mechanisms, and frequently compared on that basis.
- CJC-1295 (no DAC)Research use onlyBoth GHRH analogues. CJC-1295 without DAC is a modified GRF(1-29); sermorelin is the unmodified sequence, and is the one with an approved-drug history.
- TesamorelinFDA-approved product existsBoth GHRH analogues. Tesamorelin is the one with an approved human indication, which is the practical difference between them.
References
Each source below establishes only the specific claim noted with it, last checked 2026-08-13. Storage times reflect common handling guidance and are not established by these references.
- Pharmacokinetics of GHRH(1-29)-NH2 in healthy subjects — PMID 8329825
Biphasic clearance in humans: distribution (alpha) half-life 1.9 +/- 0.2 min, elimination (beta) half-life 10.4 +/- 0.2 min, commonly summarised as 10-20 min. Rapidly degraded by DPP-IV at the Ala2-Asp3 bond. Refined from 0.2 h to 0.17 h to match the published beta phase. Note GH stays elevated ~3 h after dosing, so the effect outlasts the peptide.
Run your own numbers
Enter the dose and concentration from your clinician, pharmacy, product instructions, or research protocol. VialPal handles the math.
As printed on the vial label
How much water you add to the vial
From your clinician, pharmacy, product instructions, or research protocol. 1000 mcg = 1 mg
Fills in a vial size this compound is commonly sold in. It does not fill in a dose — check the size against your own vial label.
Enter your numbers
Still needed: vial strength, bacteriostatic water, dose. Use the figures on your vial label and the dose from your clinician, pharmacy, product instructions, or research protocol — VialPal handles the math.
Keep this vial. VialPal holds the concentration, counts down the doses left in it, and logs the ones you actually took.
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