Semaglutide
Ozempic · Wegovy · Rybelsus
A long-acting GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management.
At a glance
- Category
- Metabolic
- Half-life
- ~7 days
- Typical vial sizes
- 2 mg · 5 mg · 10 mg
- Commonly cited dose
- 250–2400 mcg
- Frequency
- once weekly
- Routes
- Subcutaneous · Oral
A 2 mg vial, worked through.
Reconstituting a 2 mg vial of Semaglutide with 2 mL of bacteriostatic water gives 1 mg/mL. A 250 mcg dose is then:
Storage
- Lyophilised (unmixed)
- Refrigerated.
- Reconstituted
- Refrigerate at 2–8°C. Follow compounding pharmacy guidance.
What people log it against
Outcomes users commonly track alongside this compound. Listing them is not a claim that it produces them.
- Weight management
- Glycaemic control
- Appetite tracking
Read alongside Semaglutide
Compounds this one is commonly compared with, combined with, or mistaken for. Listing a pairing is not a suggestion to run them together.
- TirzepatideFDA approvedThe two most-compared incretin agonists: semaglutide targets GLP-1 alone, tirzepatide is a dual GLP-1/GIP agonist.
- AOD-9604Research use onlyBoth appear in fat-loss protocols, but AOD-9604 is a growth-hormone fragment rather than an incretin agonist, and its evidence base is far thinner.
References
Each source below establishes only the specific claim noted with it, last checked 2026-08-13. Dose ranges, frequencies and storage times reflect what circulating protocols commonly state and are not established by these references.
- FDA label — WEGOVY (semaglutide), DailyMed
"an elimination half-life of approximately 1 week" — confirms halfLifeHours 168. Label also notes semaglutide remains in circulation ~5-7 weeks after the last dose.
Run your own numbers
Pick Semaglutide from the preset list to start from a typical vial.
As printed on the vial label
How much you inject into the vial
1000 mcg = 1 mg
Fills in a common vial size and the low end of commonly cited protocols. Always check against your own vial.
on a 1 mL U-100 insulin syringe
- Concentration
- 5 mg/mL
- Volume
- 0.05 mL
- Doses in this vial
- 40
Keep this vial. VialPal holds the concentration, counts down the doses left in it, and logs the ones you actually took.
VialPal does the arithmetic — it does not tell you what to take. Dose decisions belong between you and a qualified clinician.