TB-500
Thymosin Beta-4 · TB4 · Tβ4
A synthetic fragment of Thymosin Beta-4, studied for cell migration and tissue repair. Often logged alongside BPC-157. Note that published human trials used full-length Thymosin Beta-4, not this fragment.
At a glance
- Category
- Healing & Recovery
- Half-life
- Not characterised
- Typical vial sizes
- 2 mg · 5 mg · 10 mg
- Commonly cited dose
- 2000–5000 mcg
- Frequency
- twice weekly during a loading phase
- Routes
- Subcutaneous · Intramuscular
A 2 mg vial, worked through.
Reconstituting a 2 mg vial of TB-500 with 2 mL of bacteriostatic water gives 1 mg/mL. A 2000 mcg dose is then:
- 200 units will not fit in a 1 mL syringe (100 units). Use more concentrated mixing, or split the dose.
Storage
- Lyophilised (unmixed)
- Refrigerated, protected from light.
- Reconstituted
- Refrigerate at 2–8°C. Commonly cited as usable for ~30 days.
What people log it against
Outcomes users commonly track alongside this compound. Listing them is not a claim that it produces them.
- Soft-tissue recovery
- Mobility tracking
Read alongside TB-500
Compounds this one is commonly compared with, combined with, or mistaken for. Listing a pairing is not a suggestion to run them together.
- BPC-157Research use onlyRun together in circulating protocols more often than either is run alone. Note the unit difference: TB-500 protocols are usually written in milligrams, BPC-157 in micrograms.
- Thymosin Alpha-1Prescription / compoundedBoth carry the thymosin name and are unrelated compounds — TB-500 is a thymosin beta-4 fragment, thymosin alpha-1 is a separate immune peptide with its own approvals.
References
Each source below establishes only the specific claim noted with it, last checked 2026-08-13. Dose ranges, frequencies and storage times reflect what circulating protocols commonly state and are not established by these references.
- Ruff et al., Phase I safety trial of thymosin beta-4 (2010)
IV thymosin beta-4 tolerated in 40 healthy volunteers up to 1260 mg. Used FULL-LENGTH recombinant Tβ4 (43 aa), not the TB-500 fragment, and reports no elimination half-life for the fragment — which is why halfLifeHours is null.
Run your own numbers
Pick TB-500 from the preset list to start from a typical vial.
As printed on the vial label
How much you inject into the vial
1000 mcg = 1 mg
Fills in a common vial size and the low end of commonly cited protocols. Always check against your own vial.
on a 1 mL U-100 insulin syringe
- Concentration
- 5 mg/mL
- Volume
- 0.05 mL
- Doses in this vial
- 40
Keep this vial. VialPal holds the concentration, counts down the doses left in it, and logs the ones you actually took.
VialPal does the arithmetic — it does not tell you what to take. Dose decisions belong between you and a qualified clinician.