Kisspeptin-10

KP-10 · Metastin fragment

A fragment of the kisspeptin protein studied for its upstream role in regulating reproductive hormone release.

Research use only. This compound is sold for laboratory research and is not approved by the FDA for human use. Everything below is reference information about what circulating protocols state — not a recommendation to use it.

At a glance

Category: Sexual Health
Half-life: ~4 minutes
Typical vial sizes: 5 mg · 10 mg
Commonly cited dose: 100–200 mcg
Frequency: as directed by protocol
Routes: Subcutaneous

A 5 mg vial, worked through.

Reconstituting a 5 mg vial of Kisspeptin-10 with 2 mL of bacteriostatic water gives 2.5 mg/mL. A 100 mcg dose is then:

4units(0.04 mL) — about 50 doses per vial

Storage

Lyophilised (unmixed): Refrigerated.
Reconstituted: Refrigerate at 2–8°C.

What people log it against

Outcomes users commonly track alongside this compound. Listing them is not a claim that it produces them.

Hormonal axis tracking

Read alongside Kisspeptin-10

Compounds this one is commonly compared with, combined with, or mistaken for. Listing a pairing is not a suggestion to run them together.

PT-141FDA approvedBoth touch sexual function through unrelated pathways: PT-141 acts centrally on melanocortin receptors, kisspeptin upstream of the HPG axis.

References

Each source below establishes only the specific claim noted with it, last checked 2026-08-13. Dose ranges, frequencies and storage times reflect what circulating protocols commonly state and are not established by these references.

Narayanaswamy et al., Human Reproduction 2015 — PMC4507333
Direct head-to-head infusion study in healthy men states a "plasma half-life of kisspeptin-10 of 4 min" versus "kisspeptin-54 of 27.6 min". The previous value of 0.5 h (30 min) was the kisspeptin-54 figure applied to kisspeptin-10 — a different peptide. Corrected to 0.067 h (4 min).

Run your own numbers

Pick Kisspeptin-10 from the preset list to start from a typical vial.

Your vial

Peptide in vial

As printed on the vial label

Bacteriostatic water added

How much you inject into the vial

Dose you want

mcg

1000 mcg = 1 mg

Syringe size

Start from a peptide

Fills in a common vial size and the low end of commonly cited protocols. Always check against your own vial.

Draw this much

5units

on a 1 mL U-100 insulin syringe

Concentration: 5 mg/mL
Volume: 0.05 mL
Doses in this vial: 40

Keep this vial. VialPal holds the concentration, counts down the doses left in it, and logs the ones you actually took.

VialPal does the arithmetic — it does not tell you what to take. Dose decisions belong between you and a qualified clinician.