PT-141

Bremelanotide

A melanocortin receptor agonist approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women.

FDA-approved product exists. FDA-approved prescription products containing PT-141 exist (Vyleesi). Compounded and research formulations are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness or quality.

At a glance

Category: Sexual Health
Half-life: ~2.7 hours
Typical vial sizes: 5 mg · 10 mg

Concentration by water volume

Pure arithmetic: the vial strength divided by the water added. The dose itself comes from your clinician, pharmacy, product instructions, or research protocol — enter it in the calculator below.

Vial	Water added	Concentration	Per U-100 unit
5 mg	1 mL	5 mg/mL	50 mcg
5 mg	2 mL	2.5 mg/mL	25 mcg
5 mg	3 mL	1.667 mg/mL	16.667 mcg
10 mg	1 mL	10 mg/mL	100 mcg
10 mg	2 mL	5 mg/mL	50 mcg
10 mg	3 mL	3.333 mg/mL	33.333 mcg

Storage

Lyophilised (unmixed): Refrigerated, protected from light.
Reconstituted: Refrigerate at 2–8°C.

What people log it against

Outcomes users commonly track alongside this compound. Listing them is not a claim that it produces them.

Libido tracking (approved indication for Vyleesi)

Read alongside PT-141

Compounds this one is commonly compared with or mistaken for. Listing a pairing is not a suggestion to use them together.

Kisspeptin-10Research use onlyBoth touch sexual function through unrelated pathways: PT-141 acts centrally on melanocortin receptors, kisspeptin upstream of the HPG axis.

References

Each source below establishes only the specific claim noted with it, last checked 2026-08-13. Storage times reflect common handling guidance and are not established by these references.

FDA label — VYLEESI (bremelanotide), DailyMed
"mean terminal half-life of bremelanotide is approximately 2.7 hours (range: 1.9-4.0 hours)" after single subcutaneous administration — confirms halfLifeHours 2.7.

Run your own numbers

Enter the dose and concentration from your clinician, pharmacy, product instructions, or research protocol. VialPal handles the math.

Your vial

Peptide in vial

As printed on the vial label

Bacteriostatic water added

How much water you add to the vial

Dose from your instructions

mcg

From your clinician, pharmacy, product instructions, or research protocol. 1000 mcg = 1 mg

Syringe size

Fill in a vial size

Fills in a vial size this compound is commonly sold in. It does not fill in a dose — check the size against your own vial label.

Draw this much

Enter your numbers

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